Gorter Center for High field MRI

Doctoral student of Physics or Engineering

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Posted On:
Closing On:
Dienstag, 9th Juli 2019
Sonntag, 5th Januar 2020
Department: Department of Radiology
Location: Leiden, NL

Job Description:

Job Description:
Magnetic resonance imaging (MRI) is an important diagnostic tool with excellent soft tissue contrast. Among others, diffusion is probably the most important contrast, helping to characterize tumor in type, state and grade non-invasively. In combination with proton therapy, a new emerging option for tumor treatment, MRI is a key tool for diagnosis and follow up monitoring.

As a PhD student you will engage yourself on the MRI side to develop new, robust, fast and signal-to-noise ratio efficient MR image acquisition schemes with substantial focus on advanced model-based image reconstruction to significantly enhance clinical diffusion image quality at 3T. The key is to improve this way MRI diagnosis and follow up monitoring for proton therapy.

The project will mainly be conducted in the "C.J. Gorter Center for High-field MRI “ in the Radiology Department of the university hospital Leiden (LUMC) in close collaboration with the Philips Research Laboratory in Hamburg (Germany). There is therefore the opportunity to spend some time also working in Hamburg. There is also collaboration with the proton therapy department of the Holland Proton Therapy Center in Delft, 20 km from Leiden. The Gorter center which will firm as the primary base, houses approximately 50 MRI researchers involved in MRI software and hardware development, as well as the application of the latest MRI technology in medical research and patient care. The center has a rather international character with a good balance between internationally recognized, top-end research and an excellent social working environment. The supervision for this project will be provided from the Gorter center by prof.dr. Peter Börnert and prof.dr.in. Thijs van Osch, two MRI physicists who have long experience in numerous methodological developments to MRI and their application.

Doctoral student of Physics or Engineering

The successful candidate will work with us to further improve diffusion weighted MRI data acquisition and reconstruction to improve image quality; more specifically, develop robust, motion-insensitive, geometric distortion free, water fat-resolved diffusion weighted MRI to support proton therapy applications and follow up.

The candidate should have an engineering, physics or mathematics background and should have interests to challenge the frontiers of current medical imaging. Knowledge in some numerical methods including programming skills, knowledge of some computer languages is required and/or will be acquired in the initial phase of the project. Some experience about basic concepts artificial intelligence are welcome, but are no prerequisite, because the envisaged approach can benefit from this emerging technology too. The candidate should be smart, flexible, open and eager to learn to address open and new challenges, fitting into an interdisciplinary team, dealing with methodological, hardware and clinical questions. The candidate should fluently speak English. Knowledge of Dutch would be helpful but is not required to become quickly part of the team.

The position will be advertised until a suitable candidate is found. If interested, please send your comprehensive application [incl. CV/letter of motivation/contact details of 3 references ] to Peter Börnert (p.b.boernert@lumc.nl or peter.boernert@philips.com) with the subject line PhD Position @ Gorter Center for High field MRI.


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